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The GI Effects® Comprehensive Stool Profile is an advanced stool test that provides immediate, actionable clinical information for the management of gut health. Using the most innovative technologies available, this ground-breaking stool test offers:

  • PCR (Polymerase Chain Reaction), a molecular assay optimized for stool testing assesses 24 commensal bacteria associated in the scientific literature with health and disease, and provides valuable insight into the human microbiome
  • Calprotectin, a biomarker that effectively differentiates between Irritable Bowel Syndrome (IBS) and Inflammatory Bowel Disease (IBD)*
  • O&P (ova & parasite), the gold standard for parasite identification
    • Choice of either 1 or 3 day collection, based on clinician index of suspicion for parasitic infection
    • If low/no suspicion, a one day sample will likely be adequate. If high suspicion, a 3-day sample collection is optima 
  • Enhanced Test Reporting that includes an Interpretation At-a-Glance overview that highlights clinically actionable biomarkers in three key areas of gut health: Infection, Inflammation, and Imbalance (Metabolic)




Why is this the Best Stool Test for GI Diagnostics?

Gastrointestinal function is critical for good health. Emerging evidence has associated overall GI function and gut microbiome status with a wide variety of common illnesses including, but not limited to:

  • Irritable Bowel Syndrome (IBS)
  • Inflammatory Bowel Disease (IBD)
  • Diabetes
  • Obesity
  • Cardiovascular Disease
  • Celiac and Other Malabsorption Disorders
  • Mood Disorders
  • Autoimmune
  • Autism


Assessing and normalizing GI function can have profound effects on overall health, leading to improvement in these and other conditions. The GI Effects® Comprehensive Stool Profile is a critical clinical tool in the management of patients presenting with symptoms that can be associated with compromised gut health.


What advantage does the profile offer compared to other diagnostics?

GI Effects® represents the best technical platform to assess gut health, including an optimized PCR molecular assay for anaerobic bacteria, Matrix Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) technology for identification of cultivable species, as well as premier biomarkers for stool-based gastrointestinal diagnostics.


The test report is organized so that the clinician may move through results in a logical order that enhances clinical utility, starting with an innovative Interpretation-At-A-Glance cover page.


  • Using evidence-based rules and weighted algorithms, this page synthesizes patient test results into Four Functional Pillars of clinical significance (Infection-Inflammation-Insufficiency-Imbalance) and provides a directional indication of potential therapeutic next steps in patient management.
  • Diversity Association and Relative Abundance of gut microbiota is also reported on this page, providing both a proxy measure of gut biodiversity and the patient's levels of selected key organisms relative to similar measures in a healthy cohort of individuals.


What can you expect from GI Effects Comprehensive Profile stool testing?

Functional testing can help uncover the root cause of many chronic conditions that often frustrate both physician and patient. The scope of the premier biomarkers on the GI Effects Stool Profile provides comprehensive information to the clinician for the development of strategic interventions. As identified functional imbalances and inadequacies become more normalized through targeted dietary, lifestyle, and supplementation therapeutics, intractable symptoms often improve for many patients.

Each biomarker is associated with specific pertinent therapies, but general therapeutic considerations include:


  • Discerning general evidence of bowel inflammation and providing intestinal mucosal and anti-inflammatory support
  • Addressing any identified infection with appropriate pharmacological and botanical treatments
  • Supporting commensal bacteria with pre/probiotic supplements and dietary changes


A structured diagnostic panel, like the GI Effects Comprehensive Stool Profile, is easier for patients and clinicians to implement in practice compared to the stressors associated with serial testing. The GI Effects Comprehensive Stool Profile also helps to provide enhanced clinical accuracy in determining which patients may need additional, more invasive testing.

Complete Digestive Stool Analysis

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